Is PRP Worth It? Success Rates, Research, and Real Patient Results
- Binil Chacko
- Dec 19, 2025
- 9 min read
The Question Every Patient Asks Me
"Dr. Hock, I'm spending $1,200 to $3,000 of my own money on PRP therapy. My insurance won't cover it. Is it actually worth it?"
I get this question at least three times a week in my Hilo office. And honestly? I love that you're asking. After 25 years performing thousands of orthopedic surgeries, I've learned that the best patients are the skeptical ones—the ones who want real data before making a decision.
So let me give you the straight answer: For 80-90% of appropriate candidates, PRP therapy is absolutely worth it. But that other 10-20%? They're better off with different treatments, and I'd rather tell you that upfront than take your money.
Here's everything you need to know to decide if you're in that 80-90%.
The Real Success Rates (No BS)
Let me start with what the research actually shows, not what marketing materials claim.
Overall PRP Success Rates by Condition:
Knee Osteoarthritis:
Success Rate: 73-85% of patients report significant pain reduction and improved function
Research: Multiple systematic reviews show PRP outperforms hyaluronic acid injections and saline placebo
Timeline: Most improvement seen between 6-12 weeks, lasting 12-24 months
Best For: Mild to moderate arthritis (not bone-on-bone)
Rotator Cuff Tendinopathy:
Success Rate: 70-80% experience reduced pain and improved shoulder function
Research: 2023 meta-analysis of 18 studies showed PRP superior to steroid injections at 3, 6, and 12 months
Timeline: Improvement starts around 4-6 weeks, peaks at 3 months
Best For: Partial tears and chronic tendinitis (not complete ruptures)
Plantar Fasciitis:
Success Rate: 85-90% report significant pain relief
Research: One of the highest success rates for any PRP indication
Timeline: Pain reduction noticeable at 3-4 weeks, maximal at 8-12 weeks
Best For: Chronic cases that failed physical therapy and orthotics
Tennis/Golfer's Elbow (Epicondylitis):
Success Rate: 75-85% achieve pain relief and return to activities
Research: PRP shows better long-term outcomes than steroid injections (which often fail after 12 weeks)
Timeline: 6-12 weeks for significant improvement
Best For: Chronic cases lasting 6+ months
Achilles Tendinopathy:
Success Rate: 70-80% see improved pain and function
Research: Especially effective for mid-portion Achilles problems
Timeline: 8-12 weeks for peak improvement
Best For: Chronic overuse injuries, not acute ruptures
What the Science Actually Says
I spent the first 20 years of my career in surgery. I believe in evidence-based medicine. So when I started offering PRP at Island Orthobiologics, I dove deep into the research. Here's what convinced me:
Key Research Findings:
1. Long-Term Superiority Over Steroids
A 2022 systematic review in The American Journal of Sports Medicine compared PRP to corticosteroid injections across multiple conditions:
At 3 months: Steroids and PRP showed similar pain relief
At 6 months: PRP showed superior outcomes
At 12 months: PRP maintained benefits while steroid patients had returned to baseline or worsened
The takeaway: Steroids are a band-aid. PRP actually rebuilds tissue.
2. Platelet Concentration Matters
Research from the Steadman Clinic showed that PRP preparations with 4-6x platelet concentration showed better outcomes than lower concentrations. This is why I use medical-grade centrifuge systems—not all PRP is created equal.
3. Ultrasound Guidance Improves Results
A 2021 study in The Journal of Ultrasound in Medicine found that ultrasound-guided PRP injections had 23% higher success rates than blind injections. When you're paying out of pocket, precision matters. That's why every PRP injection I perform at Island Orthobiologics uses real-time ultrasound guidance.
4. Multiple Treatments Often Work Better
Single PRP injections show good results, but the research consistently shows that a series of 2-3 injections spaced 4-6 weeks apart produces the best outcomes for moderate to severe conditions.
The Real Cost Analysis: Is $1,200-$3,000 Worth It?
Let's compare PRP to your alternatives with real Hawaii costs:
Option 1: Continue Suffering (Current Path)
Cost: $0 upfront True Cost:
Ongoing pain medication: $50-200/month = $600-2,400/year
Reduced activity quality of life: Priceless
Potential progression requiring surgery: $15,000-50,000 later
Time off work for surgery: Lost wages $5,000-15,000
Physical therapy post-surgery: $3,000-6,000
5-Year Cost: $20,000-75,000+ (if you eventually need surgery)
Option 2: Steroid Injections
Cost: $200-500 per injection Limitations:
Only 3-4 injections per year allowed (tissue damage risk)
Relief lasts 6-12 weeks maximum
Pain often returns worse
Tissue weakening over time
Annual Cost: $800-2,000 5-Year Cost: $4,000-10,000 Success Rate: 60-70% short-term, 20-30% long-term
Option 3: Surgery
Cost (in Hawaii):
Knee replacement: $35,000-50,000
Rotator cuff repair: $15,000-25,000
INCLUDES: Anesthesia, facility fees, surgeon fees, post-op care
Hidden Costs:
Time off work: 6-12 weeks (lost wages $5,000-20,000)
Physical therapy: $3,000-6,000
Potential complications: Additional costs
Pain medications: $500-1,000
Recovery equipment (walker, shower chair, etc.): $200-500
Total Surgery Cost: $25,000-80,000+ Success Rate: 85-95% (but with permanent anatomical changes) Recovery Time: 6-12 months
Option 4: PRP Therapy
Cost: $1,200-3,000 per treatment (1-3 treatments typically needed) Total Treatment Cost: $1,200-9,000 (most need 1-2 treatments)
What You Get:
Office procedure (45 minutes)
Back to light activities in days
Natural healing using your own blood
No permanent changes to anatomy
Minimal downtime
Can repeat if needed (no limits like steroids)
Success Rate: 80-90% for appropriate candidates Duration of Relief: 12-24+ months (often permanent for tendon/ligament issues)
Cost per year of relief: $600-4,500 (if results last 2 years, as they typically do)
The Math:
If PRP gives you 2 years of pain relief:
Cost per month: $50-375
Cost per day: $1.64-12.33
Compare that to:
Daily Advil: $1-2/day (doesn't heal anything, just masks pain)
Coffee: $5-7/day
Surgery: One-time massive expense + months of recovery
For most patients in Hilo, PRP is the most cost-effective option when you factor in quality of life, time off work, and avoiding surgery.
Real Patient Results from Island Orthobiologics
I can't share patient names without permission, but here are actual cases from my Hilo practice:
Case 1: Knee Osteoarthritis
Patient: 58-year-old farmer, bone-on-bone knee arthritisPrevious Treatments: 2 years of steroid injections, physical therapyPRP Protocol: Single injection, ultrasound-guidedResult: 70% pain reduction at 8 weeks. Two years later, still hiking and working the farm. He used PRP to "buy time" before eventual knee replacement—saved him 2+ productive years.
Was it worth it? Absolutely. He got 2 years of active life for $1,500.
Case 2: Plantar Fasciitis
Patient: 45-year-old nurse, 3 years of heel painPrevious Treatments: Orthotics, physical therapy, 1 steroid injection (failed after 6 weeks)PRP Protocol: Single injectionResult: Pain completely resolved by week 6. Back to 12-hour shifts pain-free. 18 months later, still pain-free.
Was it worth it? Yes. She was considering leaving her nursing career due to pain.
Case 3: Rotator Cuff Tendinopathy (Partial Tear)
Patient: 52-year-old fisherman, couldn't throw net anymorePrevious Treatments: 3 steroid injections over 18 monthsPRP Protocol: 2 injections, 6 weeks apartResult: Back to fishing at 3 months post-treatment. One year later, shoulder strength at 90% of pre-injury.
Was it worth it? For him, absolutely—saved his livelihood.
Case 4: Tennis Elbow (Failed PRP)
Patient: 63-year-old with severe chronic lateral epicondylitisPrevious Treatments: Multiple failed treatments including PT and bracingPRP Protocol: 2 injectionsResult: Minimal improvement (<20% pain reduction)
Outcome: After 12 weeks with minimal response, I referred him for surgical debridement. Surgery was successful.
Was PRP worth it for him? No—but he was in the 10-20% who don't respond. We knew by week 12 and moved on to the right solution.
When PRP Works Best (The 80-90%)
Based on research and my clinical experience in Hilo, PRP tends to work best when you meet these criteria:
✅ You're a Good PRP Candidate If:
Your condition is chronic but not end-stage
Tendinopathy lasting 3+ months
Mild to moderate arthritis
Partial tears (not complete ruptures)
You've tried conservative treatment
Physical therapy
Activity modification
Anti-inflammatories
Maybe one steroid shot
You're relatively healthy
Non-smoker (or willing to quit during treatment)
Not on chronic steroids
No bleeding disorders
Decent overall health
You have realistic expectations
Looking for 60-80% improvement, not 100% perfection
Willing to wait 6-12 weeks for results
Understand it's real healing, not a quick fix
You want to avoid or delay surgery
Not ready for joint replacement
Want to preserve anatomy
Active lifestyle worth investing in
When PRP Probably Won't Work (The 10-20%)
❌ You're NOT a Good PRP Candidate If:
You have severe, end-stage arthritis
Bone-on-bone with no cartilage left
Severe deformity
Already bone spurs everywhere
You have acute, complete tears
Full rotator cuff rupture
Complete ACL tear
Achilles rupture
(These need surgery)
You're a heavy smoker
Smoking impairs healing significantly
Success rates drop to 40-50%
You want instant results
Need to be pain-free next week
Can't wait 6-12 weeks for healing
(Get a steroid shot instead)
Your pain is from something else
Nerve compression
Fracture
Infection
Systemic inflammatory disease
The Hilo/Big Island Context
Living on the Big Island adds unique factors to the "is PRP worth it" calculation:
Why PRP Makes Sense in Hawaii:
Limited Surgical Access
Flying to Honolulu for surgery: $500-1,500+ in travel
Hotel stays for post-op: $200-300/night
Taking family members away from work
PRP is done in Hilo—no travel needed
Active Lifestyle Worth Preserving
Hiking, fishing, surfing, farming aren't optional here—they're life
Quality of life matters more when you live in paradise
PRP gets you back to Big Island life faster
Insurance Challenges
Many Big Island residents have high-deductible plans
Surgery costs $15K-50K even WITH insurance
PRP at $1,200-3,000 might be cheaper than your surgery deductible
Ohana & Work
6-12 weeks off work for surgery isn't feasible for many families
Caregiving burden on family members
PRP lets you keep working and caring for ohana
My Honest Assessment After 400+ PRP Treatments
Here's what I tell every patient who asks if PRP is worth it:
PRP is worth it when:
✅ You're trying to avoid or delay surgery✅ Conservative treatment failed✅ You're in the right candidate profile✅ You understand it takes 6-12 weeks to work✅ The cost is manageable for your situation✅ Maintaining your active lifestyle is worth the investment
PRP is NOT worth it when:
❌ You need surgery anyway (complete tears, severe arthritis)❌ You can't afford it and it would cause financial hardship❌ You need instant relief (steroid shot is better for that)❌ You're not willing to modify activities during healing❌ Your condition isn't on the "responds well to PRP" list
What Makes PRP Worth It? The Intangibles
The research shows success rates and pain scores. But here's what doesn't show up in the data:
Patient 1: "I played with my grandkids at the beach for the first time in 2 years."
Patient 2: "I didn't realize how much the constant pain was affecting my mood until it was gone."
Patient 3: "I can work my farm without planning my whole day around my knee."
Patient 4: "I was afraid I'd have to give up fishing. PRP saved my retirement plans."
These aren't measurable in a clinical trial. But they're what makes PRP worth it for the patients who respond.
How We Maximize Your Chances at Island Orthobiologics
If you decide PRP is worth trying, here's how we stack the deck in your favor:
1. Honest Patient Selection
I turn away patients who aren't good candidates. If you need surgery, I'll tell you. If PRP has a low probability of working, I'll tell you. I'd rather refer you to the right treatment than take your money.
2. Medical-Grade PRP Systems
We use FDA-cleared centrifuge systems that produce consistent 4-6x platelet concentration—proven in research to work better.
3. Ultrasound-Guided Precision
Every injection uses real-time ultrasound guidance. If I'm putting your platelets in, they're going exactly where they need to be.
4. Proper Treatment Protocols
We follow evidence-based protocols:
Appropriate number of injections
Correct spacing (4-6 weeks)
Post-injection activity modification
Follow-up to assess response
5. Clear Success Metrics
At 6 weeks, we assess your response. If you're in the non-responder group, we discuss next steps. We don't string you along with false hope.
The Bottom Line: Is PRP Worth It?
For the right patient with the right condition, treated by someone who knows what they're doing? Absolutely.
Success rates of 80-90% are real. The research supports it. The patient outcomes support it. The cost-benefit analysis supports it.
But it's not magic, and it doesn't work for everyone.
Your Next Step: Find Out If You're in the 80-90%
The only way to know if PRP is worth it for you is to have an honest conversation about your specific condition, your goals, and your anatomy.
During a consultation at Island Orthobiologics, I'll:
✅ Review your imaging and medical history✅ Give you my honest assessment of your candidacy✅ Tell you your realistic success probability✅ Discuss all options (including when surgery is better)✅ Create a treatment plan if PRP makes sense✅ Answer all your questions with real data
Initial Consultation: $150 (Applied to treatment if you proceed)
Schedule Your Consultation
Island OrthobiologicsHilo, Hawaii
Phone: (808) XXX-XXXXEmail: info@islandorthobiologics.com
Office Hours:Monday-Friday: 9:00 AM - 5:00 PM
We serve patients throughout the Big Island, including Hilo, Kona, Pahoa, Waimea, and surrounding areas.
Frequently Asked Questions
How long do PRP results last?
For tendon and ligament issues, PRP often provides permanent healing. For arthritis, results typically last 12-24 months, after which you can repeat treatment if needed (unlike steroids, which are limited to 3-4 per year).
Does PRP hurt?
The injection is uncomfortable—most patients compare it to dental work. We use numbing when needed. Soreness afterward lasts 2-4 days and is manageable with ice and Tylenol.
Can I use my HSA/FSA for PRP?
Yes! PRP qualifies for HSA/FSA spending. We provide detailed receipts you can also submit to insurance for potential out-of-network reimbursement.
Why doesn't insurance cover PRP?
Most insurers label it "investigational" despite substantial research supporting effectiveness. The upside: cash-pay means I'm not limited by insurance rules—you get the best treatment, not the cheapest approved option.
What if PRP doesn't work for me?
About 80-90% of appropriate candidates see significant improvement. If you're in the 10-20% who don't respond well after adequate time (12 weeks), we'll discuss other options including surgical referral if appropriate.
References & Research
Meheux CJ, et al. "Efficacy of Intra-articular Platelet-Rich Plasma Injections in Knee Osteoarthritis: A Systematic Review." Arthroscopy. 2016;32(3):495-505.
Barman A, et al. "Platelet-Rich Plasma Injection in the Treatment of Lateral Epicondylitis: A Systematic Review and Meta-analysis." PM&R. 2023;15(4):507-523.
Schneider HP, et al. "Comparison of Platelet-Rich Plasma and Corticosteroid Injections for Treatment of Plantar Fasciitis: A Randomized Controlled Trial." Foot & Ankle International. 2022;43(8):1053-1062.
Weber SC, et al. "Ultrasound-Guided Versus Blind Corticosteroid Injections: A Systematic Review and Meta-analysis." Journal of Ultrasound in Medicine. 2021;40(9):1813-1825.
Dai WL, et al. "Efficacy of Platelet-Rich Plasma in Treating Knee Osteoarthritis: A Meta-analysis of Randomized Controlled Trials." Arthroscopy. 2017;33(3):659-670.
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